LatchBio · San Francisco or Remote
Skills: Python
AI Biologics - Immunology Latch builds rigorous scientific benchmarks (benchmarks.bio http://benchmarks.bio) for AI agents across biology. We work with frontier labs and pharma to measure whether agents can handle real biological workflows: the messy, multi-layer reasoning that matters in the field. We’re seeking an AI Biologist to join our Immunology team, pushing what AI can achieve in immune biology and vaccine development. About the Role. You will be the scientific authority on ground truth, testing whether agents can reason like an expert immunologist. AI agents today struggle to interpret raw immune data, separate real biology from gating and batch artifacts, and make calls an expert would defend in a lab meeting or program review. You’ll work with scientists and engineers to build the tasks and datasets behind our benchmarks, and your judgment will set the standard agent outputs are held to. Build the task - Turn real immunology workflows into tasks with clear answers: immune profiling, vaccine immunogenicity, T and B cell responses, inflammation and autoimmunity readouts, and immune cell engineering - Write gold-standard answers from raw data, with tolerances that reflect real donor, assay, and gating variability - Curate data: flow and spectral cytometry, single-cell and CITE-seq, TCR/BCR repertoires, cytokine panels, serology and neutralization titers, ELISpot Set the hard calls - Test whether agents can tell real biology from artifact: a doublet or spillover “population,” a batch effect, a clonal expansion that’s really sampling depth - Test whether agents separate immunogenicity from protection, activation from exhaustion, and mouse findings from human relevance Judge the agent - Challenge conclusions that sound right but wouldn’t survive expert review - Pinpoint where agents go wrong, what an expert would do instead, and what evidence would change the call - Reward explicit uncertainty over confident guesses Requirements - PhD in immunology, vaccinology…
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