LatchBio · San Francisco (preferred)
Skills: Python
AI Biologist - Longevity Latch builds rigorous scientific benchmarks (benchmarks.bio http://benchmarks.bio) for AI agents across biology. We work with frontier labs and pharma to measure whether agents can handle real biological workflows: the messy, multi-layer reasoning that matters in the field. We’re seeking an AI Biologist to join our Longevity team, pushing what AI can achieve in aging biology. About the Role. You will be the scientific authority on ground truth, testing whether AI agents can reason like an expert aging biologist. Today’s agents struggle to separate biological age from chronological age, spot confounds that make aging signals look real, and judge which longevity claims hold up. Working with real published and public datasets, you’ll build the tasks behind our benchmarks, starting with aging biomarkers and the hallmarks of aging. Your judgment sets the standard agents are held to. Build the task - Turn real aging research questions into tasks, and write gold-standard answers an expert would defend - Curate data across molecular and population scales: DNA methylation, transcriptomics, proteomics, single-cell, longitudinal cohorts and biobanks - Build tasks around aging clocks, biological age prediction, senescence, epigenetic drift, and mitochondrial dysfunction - Partner with software engineers to turn your judgment into workflows Set the hard calls - Test whether agents catch cell-type composition, batch effects, and age imbalance between groups - Test whether agents know when findings in worms, mice, or cell models won’t translate to human aging - Adjudicate contested longevity claims: what the data support, what they don’t, and what would settle it Judge the agent - Challenge reasoning that sounds right but wouldn’t survive peer review or a go/no-go decision - Pinpoint where agents fail, what an expert would do instead, and what evidence would change the call - Reward calibrated uncertainty over confident guesses Requirements - Master’s or P…
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